原著論文1
Ishiguro N, Maeda K, Saito A et al.
Establishment of a set of double transfectants coexpressing organic anion transporting polypeptide 1B3 and hepatic efflux transporters for the characterization of the hepatobiliary transport of telmisartan acylglucuronide
Drug Metab Dispos
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, 796-805
(2008)
原著論文2
Matsushima S, Maeda K, Hayashi H et al.
Involvement of multiple efflux transporters in hepatic disposition of fexofenadine
Mol Pharmacol
(2008)
原著論文3
Saji T, Kikuchi R, Kusuhara H et al.
Transcriptional regulation of human and mouse organic anion transporter 1 by hepatocyte nuclear factor 1 alpha/beta
J Pharmacol Exp Ther
, 324
(2)
, 784-790
(2007)
原著論文4
Enokizono J, Kusuhara H and Sugiyama Y
Effect of breast cancer resistance protein (Bcrp/Abcg2) on the disposition of phytoestrogens
Mol Pharmacol
, 72
(4)
, 967-975
(2007)
原著論文5
Kikuchi R, Kusuhara H, Hattori N et al.
Regulation of tissue-specific expression of the human and mouse urate transporter 1 gene by hepatocyte nuclear factor 1 alpha/beta and DNA methylation
Mol Pharmacol
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, 1619-1625
(2007)
原著論文6
Yamasaki Y, Ieiri I, Kusuhara H et al.
Pharmacogenetic Characterization of Sulfasalazine Disposition Based on NAT2 and ABCG2 BCRP) Gene Polymorphisms in Humans.
Clin Pharmacol Ther
(2008)
原著論文7
Ieiri I, Suwannakul S, Maeda K et al.
SLCO1B1 (OATP1B1, an uptake transporter) and ABCG2 (BCRP, an efflux transporter) variant alleles and pharmacokinetics of pitavastatin in healthy volunteers.
Clin Pharmacol Ther
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(5)
, 541-547
(2007)
原著論文8
Ishiguro N, Maeda K, Shitara Y et al.
Predominant contribution of OATP1B3 to the hepatic uptake of telmisartan, an angiotensin II receptor antagonist, in humans.
Drug Metab Dispos
, 34
, 1109-1115
(2006)
原著論文9
Yamashiro W, Maeda K, Hirouchi M et al.
Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist of the antiotensin II AT1-receptor, in humans.
Drug Metab Dispos
, 34
, 1247-1254
(2006)
原著論文10
Kikuchi R, Kusuhara H, Hattori N et al.
Regulation of the Expression of Human Organic Anion Transporter 3 by Hepatocyte Nuclear Factor 1{alpha}/beta and DNA Methylation.
Mol Pharmacol
, 70
, 887-896
(2006)
原著論文11
Enokizono J, Kusuhara H and Sugiyama Y
Involvement of breast cancer resistance protein (BCRP/ABCG2) in the biliary excretion and intestinal efflux of troglitazone sulfate, the major metabolite of troglitazone with a cholestatic effect
Drug Metab Dispos
, 35
, 209-214
(2007)
原著論文12
Shikata E, Yamamoto R, Takane H et al.
Human organic anion transporter (OCT1 and OCT2) gene polymorphisms and therapeutic effects of metformin
J Hum Genet
, 52
, 117-122
(2007)
原著論文13
Nishida N, Tanabe T, Takasu M et al.
Further development of multiplex SNP typing method, DigiTag2 assay
Anal Biochem
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, 78-85
(2007)
原著論文14
Hirano M, Maeda K, Hayashi H et al.
Bile salt export pump (BSEP/ABCB11) can transport a nonbile acid substrate, pravastatin
J Pharmacol Exp Ther
, 314
, 876-882
(2005)
原著論文15
Hirano M, Maeda K, Matsushima S et al.
Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin
Mol Pharmacol
, 68
, 800-807
(2005)
原著論文16
Matsushima S, Maeda K, Kondo C et al.
Identification of the Hepatic Efflux Transporters of Organic Anions Using Double-Transfected MDCKII Cells Expressing Human OATP1B1/Multidrug Resistance-Associated Protein 2, OATP1B1/Multidrug Resistance 1, and OATP1B1/Breast Cancer Resistance Protein
J Pharmacol Exp Ther
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, 1059-1067
(2005)
原著論文17
Mita S, Suzuki H, Akita H et al.
Vectorial transport of unconjugated and conjugated bile salts by monolayers of LLC-PK1 doubly transfected with human NTCP and BSEP or with rat Ntcp and Bsep
Am J Physiol Gastrointest Liver Physiol
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, 550-556
(2006)
原著論文18
Shimizu M, Fuse K, Okudaira K et al.
Contribution of oatp (organic anion-transporting polypeptide) family transporters to the hepatic uptake of fexofenadine in humans
Drug Metab Dispos
, 33
, 1477-1481
(2005)
原著論文19
Hayashi H, Takada T, Suzuki H et al.
Two common PFIC2 mutations are associated with the impaired membrane trafficking of BSEP/ABCB11
Hepatology
, 41
, 916-924
(2005)
原著論文20
Takane H, Miyata M, Burioka N et al.
Severe toxicities after irinotecan-based chemotherapy in a patient with lung cancer: a homozygote for the SLCO1B1*15 allele
Ther Drug Monit
, 29
, 666-668
(2007)
